Noradrenaline (norepinephrine) as acid tartrate monohydrate, concentrate for i.v. injection

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Noradrenaline MYX.

It does not contain all the available information.

It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits.

Your doctor has weighed the risks of you being given Noradrenaline MYX against the benefits they expect it will have for you.

If you have any concerns about being given this medicine, ask your doctor or pharmacist.

Keep this leaflet in a safe place. You may need to read it again.

What Noradrenaline MYX is used for

Noradrenaline MYX is only given by a doctor or nurse in an emergency situation, usually in hospital as a result of serious conditions which cause a dramatic drop in blood pressure.

Such conditions could be:

  • a heart attack
  • infection in the blood
  • severe reaction to a drug
  • severe reaction to a blood transfusion
  • allergic reactions.

Noradrenaline MYX is used to restore blood pressure back to normal.

This medicine belongs to a group of medicines called sympathomimetic amines.

It works by making the heart beat more forcefully and constricting blood vessels.

This results in a higher blood pressure and greater blood flow to the heart and other organs of the body.

Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason.

There is no evidence that Noradrenaline MYX is addictive.

This medicine is available only with a doctor’s prescription.

Before you are given Noradrenaline MYX

When you must not be given it

You should not be given Noradrenaline MYX if you have an allergy to:

  • any medicine containing noradrenaline (norepinephrine)
  • any other similar medicines such as adrenaline, phenylephrine, pseudoephedrine
  • any of the ingredients listed at the end of this leaflet.

Some of the symptoms of an allergic reaction may include:

  • shortness of breath
  • wheezing or difficulty breathing
  • swelling of the face, lips, tongue or other parts of the body
  • rash, itching or hives on the skin.

You should not be given Noradrenaline MYX if:

  • you have low blood pressure due to low blood volume
  • you have blood clots in certain vessels.

If given in these cases, it can further reduce blood supply to important organs.

If you are not sure whether you should be given Noradrenaline MYX, talk to your doctor or pharmacist.

Before you are given it

Tell your doctor or pharmacist if you have allergies to:

  • any other medicines
  • any other substances, such as foods, preservatives or dyes.

Tell your doctor or pharmacist if you have asthma.

Tell your doctor or pharmacist if you are pregnant or intend to become pregnant. Your doctor or pharmacist will discuss the possible risks and benefits of you being given Noradrenaline MYX during pregnancy.

Tell your doctor or pharmacist if you are breast-feeding or plan to breast-feed. Your doctor or pharmacist will discuss the possible risks and benefits of using Noradrenaline MYX during breast-feeding. It is not known whether Noradrenaline MYX passes into breast milk.

If you have not told your doctor about any of the above, tell them before you start receiving Noradrenaline MYX.

Tell your doctor if you have any medical conditions before being given Noradrenaline MYX.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.

Some medicines and Noradrenaline MYX may interfere with each other. These include:

  • antidepressants including moclobemide, imipramine and amytriptilline.

These medicines may increase the effects of Noradrenaline MYX. You may need different amounts of this medicine, or you may need to take different medicines. Your doctor or pharmacist will advise you.

Your doctor and pharmacist may have more information on medicines to be careful with or avoid while being given Noradrenaline MYX.

How Noradrenaline MYX is given

How much is given

Your doctor will decide what dose you will receive. This depends on your condition and how you respond to Noradrenaline MYX. Often, the dose is adjusted according to how the medicine is affecting your blood pressure.

How it is given

Noradrenaline MYX is diluted and given slowly as an infusion (a drip) into a large vein. It will usually be given to you by a doctor.

How long it is given for

This medicine is given until blood pressure and blood circulation to all organs is back to normal and remains normal even when the medicine is no longer given.

If you take too much (overdose)

As Noradrenaline MYX is given to you in hospital under the supervision of your doctor; it is very unlikely that you will receive an overdose. Symptoms would include:

  • headache
  • dizziness
  • sensitivity to light
  • chest pain
  • sweating and pale skin
  • vomiting
  • trouble breathing.

Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much Noradrenaline MYX. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

Side effects

All medicines can have side effects. Sometimes they are serious, most of the time they are not.

If you are over 65 years of age you may have an increased chance of getting side effects.

Do not be alarmed by the following lists of side effects. You may not experience any of them.

Tell your doctor if you do not feel well, or if you experience any of the following while you are being given Noradrenaline MYX.

  • skin and tissue damage close to the site of injection
  • anxiety
  • headache
  • dizziness
  • difficulty breathing
  • high blood pressure
  • low or irregular heart-beat
  • tingling or numbness in the feet
  • coldness, numbness or discolouration of your limbs.

After using Noradrenaline MYX


Noradrenaline MYX injection will be stored in the pharmacy or on the ward. The injection is kept in a cool dry place, protected from light. Store below 25°C.

Product description

What it looks like

Noradrenaline MYX is a clear liquid in a glass ampoule.

It is available in two sizes: 2 mg/2 mL and 4 mg/4 mL; in carton packs of 10 ampoules. Each ampoule is for single use in one patient only.


The active ingredient in Noradrenaline MYX is noradrenaline (norepinephrine) acid tartrate monohydrate. There is 1 mg of noradrenaline (norepinephrine, as acid tartrate monohydrate) in each 1 mL of Noardrenaline MYX.

Noradrenaline MYX also contains:

  • Sodium chloride
  • Water for injections.


Mayne Pharma International Pty Limited
ABN 88 007 870 984
1538 Main North Road
Salisbury South SA 5106

Australian Registration Numbers
2 mg/2 mL: AUST R 232701
4 mg/4 mL: AUST R 232700

This leaflet was prepared in November 2016.

MYX is a registered trade mark of Mayne Pharma International Pty Limited.

Published by MIMS March 2017

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