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Moviprep Powder for oral solution

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Consumer Medicine Information

Please read this leaflet carefully because it contains important information for you. If you have any questions please ask your doctor or pharmacist.


MOVIPREP is a lemon flavoured powder contained in four sachets. There are two large sachets (Sachet A) and two small sachets (Sachet B). You need all these for one treatment.

What is MOVIPREP used for?

You are taking MOVIPREP to make your bowels clean so that they are ready for examination or surgery. MOVIPREP works by emptying the contents of your bowels, so you should expect to have watery bowel movements.

Before you take MOVIPREP

Do not take MOVIPREP if your doctor has told you that you have:

  • an obstruction in your intestine (gut)
  • a perforated gut wall
  • paralysis of the gut (often happens after an operation to the abdomen)
  • If you suffer from phenylketonuria (This is a hereditary inability of the body to use a particular amino acid. MOVIPREP contains a source of phenylalanine)
  • your body is unable to produce enough glucose-6-phospho-dehydrogenase
  • severe inflammatory bowel disease, like ulcerative colitis, Crohn’s disease, or toxic megacolon
  • an allergy to macrogol or other ingredients in the product.

If you are pregnant or breast feeding, talk to your doctor before you take MOVIPREP.

If you are taking other oral medicines, speak to your doctor. Most other oral medicines should be taken at least one hour before or one hour after taking MOVIPREP because they may be flushed through your digestive system and not work so well. However some medicines such as sustained release preparations or medicines with a narrow therapeutic window, such as the contraceptive mini-pill, may need to be taken more than one hour before or after MOVIPREP. Contraceptive cover from the oral contraceptive pill is likely to be incomplete if it is taken at any time during the process of bowel cleansing with MOVIPREP (an hour before the first dose of MOVIPREP until after the investigation). Therefore an alternative method of contraception should be used for the length of the cycle when MOVIPREP is taken.

Patients with insulin-dependent diabetes should consult their physician prior to use of MOVIPREP. Only liquids should be consumed during usage of MOVIPREP, therefore insulin dosing should be balanced accordingly.

How to use MOVIPREP

This pack contains 2 clear bags each containing two sachet pairs: sachet A and Sachet B.

Each pair of sachets (A and B) is to be dissolved in one litre of water. This pack is therefore enough to make up two litres of MOVIPREP solution.

Before your take MOVIPREP, please read carefully the following instructions. You need to know

  • When to take MOVIPREP
  • How to prepare MOVIPREP
  • How to drink MOVIPREP
  • What you should expect to happen

When to take MOVIPREP

Your doctor, nurse or pharmacist may tell you when to take MOVIPREP. Your treatment with MOVIPREP must be completed before your clinical examination and can be taken:

Either divided as 1 litre of MOVIPREP in the evening before and 1 litre in the early morning of the day of the examination,

or2 litres in the evening before the examination,

or 2 litres early in the morning of an examination booked late in the same day.

Important: Do not take any solid food from when you start to take MOVIPREP until after the examination.

How to prepare MOVIPREP

  • Open one clear bag and remove Sachets A and B
  • Add the contents of BOTH sachet A and B to a 1 litre container
  • Pour 1 litre of water into the container and stir until all the powder has dissolved and the MOVIPREP solution is clear or slightly hazy. This may take up to 5 minutes.

How to drink MOVIPREP

Drink the first litre of the MOVIPREP solution over one to two hours. Try to drink a glassful every 10-15 minutes.

When you are ready, make up and drink the second litre of MOVIPREP solution made up with the contents of the Sachets A and B from the remaining bag.

During the course of this treatment drink a further one litre of clear liquid to prevent you from feeling very thirsty and becoming dehydrated. Clear liquids include: Water, clear soup, tea or coffee (without milk or non-dairy creamer), all of the following liquids which are not coloured red or purple: fruit juices without pulp, carbonated or non carbonated soft drinks, fruit flavoured cordials Note: patients should not drink anything coloured red or purple.

What you should expect to happen

When you start drinking the MOVIPREP solution, it is important that you stay close to a toilet. At some point, you will start to experience watery bowel movements. This is quite normal and indicates the MOVIPREP is working. The bowel movements will stop soon after you have finished drinking.

If you follow these instructions, your bowel will be clear, and this will help you to have a successful examination.


MIOVIPREP should not be taken by children aged below 18 years.

What about side effects?

Like all medicine, MOVIPREP can have side effects.

You may feel full in the stomach, a little nauseous, have stomach pains or soreness around the anus, and if this happens take MOVIPREP more slowly until these feelings stop. If the feelings do not stop, consult you pharmacist or doctor. There is a possibility of vomiting. If you feel other unpleasant side effects tell your doctor or pharmacist.

Blood sodium levels could also decrease, particularly if you take medicines that affect your kidneys, such as ACE inhibitors and diuretics used for the treatment of heart disease. Very low blood sodium levels can cause convulsions (fits)

If your blood sodium levels change, you may feel breathless, very thirsty with a severe headache, or get puffy ankles.

There have been rare reports of severe allergic reactions to Macrogol 3350 (an ingredient in MOVIPREP). Signs of severe, life threatening allergic reaction include sudden signs of allergy, such as rash, itching or hives on the skin, swelling of the face, lips, tongue or other parts of the body, shortness of breath, wheezing or trouble breathing.

If you experience any of these reactions, stop taking MOVIPREP and tell your doctor immediately, or go to the Accident & Emergency department at your nearest hospital.

How to store MOVIPREP

Keep MOVIPREP sachets at room temperature (below 25ºC), stored in their original packaging, and do not use after the expiry date on the label.

After you have dissolved MOVIPREP in the water, the solution may be stored (keeping covered) at room temperature (below 25ºC), or put it in the fridge (2-8ºC). Do not freeze the solution and do not keep it for more than 24 hours.

Keep all medicines away from children.

What MOVIPREP contains

Sachet A contains these active substances:

  • Macrogol 3350 – 100 g
  • Sodium sulphate anhydrous – 7.5 g
  • Sodium chloride – 2.691 g
  • Potassium chloride – 1.015 g

Sachet B contains these active substances:

  • Ascorbic acid 4.7 g
  • Sodium ascorbate 5.9 g

The concentration of electrolyte ions when both sachets are made up to 1 litre of solution is as follows:

  • Sodium 181.6 mmol/L (of which no more than 56.2 mmol is absorbable)
  • Sulfate 52.8 mmol/L
  • Chloride 59.8 mmol/L
  • Potassium 14.2 mmol/L
  • Ascorbate 29.8 mmol/L

MOVIPREP also contains lemon flavour, aspartame and potassium acesulfame as sweeteners.

AUST R 155398

Date: March 2010

Norgine Pty Limited, 3/14 Rodborough Road, Frenchs Forest NSW 2086

Published by MIMS December 2011