Cilicaine Syringe 1.5 Suspension for injection


procaine benzylpenicillin (procaine penicillin)

Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about CILICAINE. It does not contain all the available information. It does not take place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of using CILICAINE against the benefits this medicine is expected to have for you.

If you have any concerns about this medicine, ask your doctor or pharmacist.

Keep this leaflet with your medicine. You may need to read it again.

What is CILICAINE used for

The name of your medicine is CILICAINE syringe injection.

CILICAINE is a type of antibiotic and belongs to the group of medicines called penicillins. It contains a penicillin, as an active ingredient, which is called Procaine benzylpenicillin (procaine penicillin).

CILICAINE syringe injection is available as a 1.5 gram disposable syringe with sterile swabs.

CILICAINE is used to treat infections in different parts of the body caused by bacteria. It works by killing the bacteria that are causing the infection. It will not work against infections caused by viruses such as colds or the flu.

Your doctor may have prescribed this medicine for another purpose.

Ask your doctor if you have any questions about why CILICAINE has been prescribed for you.

CILICAINE is only available with a doctor’s prescription.

Before using it

When you must not be given it

Do not use CILICAINE if you have ever had an allergic reaction to:

  • CILICAINE syringe injection or any other penicillin.
  • Any of the other ingredients in CILICAINE listed at the end of this leaflet.

You must tell your doctor if you have had an allergic reaction to cephalosporins. You may have an increased chance of being allergic to CILICAINE if you are allergic to cephalosporins.

Some of the symptoms of an allergic reaction may include skin rash and itching. Other reactions may include nausea, vomiting and diarrhoea.

Tell your doctor if you have suffered from any of the allergic conditions in the past due to the use of penicillin.

You must also tell your doctor if:

  1. You are allergic to any other medicines, foods, dyes or preservatives.
  2. You are pregnant or intend to become pregnant.
  3. You are breast-feeding or plan to breast feed.
    Like most medicines, CILICAINE is not recommended in pregnancy and during breast-feeding. Your doctor will discuss the possible risks and benefits of using CILICAINE during pregnancy and breast-feeding.

When you must not be given it

Do not use CILICAINE if:

  • the packaging shows sign of tampering or the seal is broken.
  • the expiry date printed on the pack has passed.
    The medication may have no effect at all, or worse, it may give an entirely unexpected effect if you use it after the expiry date.

Taking other medicines

Tell your doctor (or pharmacist) if you are taking any other medicines including probenecid, a medicine used to treat gout.

This includes any that you buy without a prescription from a pharmacy, supermarket or health food shop.

Some medicines may affect the way others work. Your doctor or pharmacist can tell you what to do when CILICAINE is given with other medicines.

Talk to your doctor about the need for an additional method of contraception while on a course of CILICAINE. Some antibiotics may decrease the effectiveness of some birth control pills, although this has not been shown with CILICAINE.

How much is given

CILICAINE is given as a deep injection into a large muscle.

CILICAINE must only be given by a doctor or nurse.

How much to inject

The usual dose is:

Adults: 1.5 g daily for two to five days.
For the treatment of Gonorrhoea or Syphilis a dose of 1 g daily for 7 to 14 days or up to 4.8 g as a single session treatment usually administered with probenecid.

Children: 1/4 or 1/2 adult dose is usually sufficient for under 3 or over 3 years, respectively.

How long to use it for

Your doctor will tell you how long the course of CILICAINE will last. The whole course must be given. Do not cease CILICAINE even if you feel better.

Your infection and symptoms may return.

If you forget to take it

If you forget to go for CILICAINE administration, go to your doctor as soon as you remember and then go back to your normal visits.

If you take too much (overdose)

Telephone your doctor or Poisons Information Centre (phone 13 11 26) if you think that you or anyone else may have been given too much CILICAINE. Do this even if there are no signs of discomfort or poisoning.

Keep the telephone numbers of these places handy.

While you are using it

Things you must do

If your symptoms do not improve within few days, or if they become worse, tell your doctor.

If you develop any form of skin rash and/or itching or difficulty in breathing while using CILICAINE, contact your doctor immediately.

If you develop severe diarrhoea tell your doctor immediately.

Do this even if it occurs several weeks after you have stopped using CILICAINE.

If you become pregnant while you are using this medicine tell your doctor.

If you have to get any blood or urine tests done tell your doctor and nurse that you are using CILICAINE.

Tell all your doctor(s), dentist and pharmacist(s) who are treating you that you are on a course of CILICAINE.

Tell your doctor if you feel that this medicine is not helping your condition.

Tell your doctor if, for any reason, it has not been used exactly as prescribed. Otherwise, your doctor may think that it was not effective and change your treatment unnecessarily.

Things you must not do

Do not cease your CILICAINE course until it is finished, even if you feel better. Your infection and symptoms may not clear completely and it may return.

Do not administer this medicine to anyone else even if their symptoms seem similar to yours.

Do not use CILICAINE to treat other conditions unless your doctor tells you. Your doctor has prescribed CILICAINE especially for you and your condition. If you use it for another condition, it may not work or make the condition worse.

Things to be careful of

Tell your doctor if you get vaginal itching or discharge, sore mouth or tongue. This is due to a fungal infection called Thrush. Sometimes use of this medicine allows fungi to grow, as CILICAINE is ineffective against fungi.

If you get diarrhoea, nausea or vomiting, tell your doctor.

Take care while driving or operating machinery until you know how CILICAINE affects you. CILICAINE generally does not affect your ability to drive a car or operate machinery. However, as with many other medicines, CILICAINE may also cause dizziness, drowsiness and/or tiredness in some people.

Side Effects

Tell your doctor or pharmacist if you do not feel well while you are using CILICAINE. CILICAINE helps most people with infections but it may have some unwanted side effects in a few people.

Side effects reported by some people using CILICAINE include:

  • diarrhoea
  • nausea & vomiting
  • skin rash
  • difficulty in breathing

CILICAINE may cause other side effects.

If you have any other side effects, check with your doctor.

Do not be alarmed by this list of possible side effects. You may
not experience any of them.

While using it


Keep CILICAINE syringe injection where young children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Store CILICAINE syringe 2 – 8°C. DO NOT FREEZE.

Do not leave CILICAINE syringe in the car or on windowsills. Heat can destroy some medicines.


If your doctor tells you to stop using CILICAINE or it has passed its expiry date, ask your pharmacist what to do with any CILICAINE syringe left over.

Product Description

What it looks like

CILICAINE injection is a slightly viscous white suspension with a faint odour characteristic of penicillin.


Active ingredient:

Procaine benzylpenicillin (procaine penicillin) 1.5 g per 3.4 mL.

Inactive ingredients:

Polysorbate 80, sodium citrate, and water for injections. CILICAINE 1.5 syringe injection is preservative free.

Australian Registration number:
CILICAINE 1.5 syringe injection
AUST R 288818.


Aspen Pharma Pty Ltd
34-36 Chandos Street
St Leonards NSW 2065

This leaflet was revised in June 2017

Published by MIMS November 2017


Receive the latest news

Subscribe To Our Weekly Newsletter

Get notified about new articles