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Ovarian cancer: what you need to know

front view of female reproductive system

What is ovarian cancer?

Ovarian cancer is cancer of a woman’s ovary or ovaries. The ovaries are located on either side of the uterus (womb) and produce eggs and female sex hormones. Ovarian cancer most commonly affects women who've passed their menopause, but younger women can also be affected. It is the 8th most common cancer affecting women in Australia.

What are the symptoms?

Some of the symptoms of ovarian cancer include:

  • pelvic pain or discomfort;
  • abdominal bloating, swelling or fullness;
  • nausea and loss of appetite;
  • changes in bowel habits, including diarrhoea or constipation;
  • changes in bladder habits, including urinary urgency (an urgent need to empty the bladder);
  • changes in your menstrual cycle, or bleeding after you have gone through menopause; and
  • pain during intercourse.

While these non-specific symptoms are often due to less serious diseases, they can indicate ovarian cancer, especially if the symptoms are persistent or getting worse. But because many women don’t experience any symptoms at all early on, and if they do, the symptoms are often vague and tend to mimic other problems, ovarian cancer is sometimes not detected until the cancer is advanced and at a stage when cure is less likely.

Who is at risk of ovarian cancer?

Some factors may put you at a slightly higher risk of developing ovarian cancer, while other factors can reduce your risk. Factors that can increase your risk include:

  • a family history of ovarian or breast cancer;
  • age — your risk increases as you get older, with 90 per cent of ovarian cancers occurring in women over the age of 45;
  • infertility; and
  • taking oestrogen-only hormone replacement therapy for an extended length of time.

Having at least one pregnancy seems to reduce your risk of ovarian cancer, and breast feeding your baby for a year or more can also help reduce your risk. Similarly, taking the oral contraceptive pill may decrease your risk. In fact, taking the pill for 3 or more years can reduce the risk of ovarian cancer by 30 to 50 per cent.

How is ovarian cancer diagnosed?

There are a number of tests that are used to help diagnose ovarian cancer, including ultrasounds, X-rays and blood tests. If these tests suggest that ovarian cancer is likely, an operation is usually needed to confirm the diagnosis. If an ovarian tumour is discovered during the operation, surgery to remove the cancer can be performed at the same time.

What treatments are available?

In most cases, ovarian cancer is treated initially with surgery to remove the cancer, followed by chemotherapy to kill any remaining cancer cells in the body. Radiotherapy is also sometimes used to treat ovarian cancer.

What is the outlook for women with ovarian cancer?

The outlook for women with ovarian cancer depends on the type of tumour and whether it has spread to other areas of the body. There are 4 main types of ovarian tumours:

  • epithelial tumours, which are the most common type and usually affect older women;
  • germ cell tumours, which are more common in younger women;
  • stromal tumours, which can occur at any age; and
  • borderline tumours, which don’t spread as quickly as other forms of ovarian cancer.

Germ cell tumours, stromal tumours and borderline tumours respond well to treatment and can usually be cured. Unfortunately, the outlook for women with epithelial tumours is not always as good; however, women with early epithelial tumours that have not spread have a good chance of complete recovery.


 

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