Ginkgo biloba has no beneficial effect on memory and related mental functions in healthy older adults, according to US research.
Researchers gave 14 tests of learning, memory, attention and concentration to 230 mentally and physically healthy volunteers over age 60. Mental functions were rated on subjective scales by participants and their companions. The double-blind study gave ginkgo to one group and a dummy medicine (placebo) to the other.
Manufacturers claimed beneficial effects could be noticed after 4 weeks.
After 6 weeks, participants re-took tests and mental functions were re-rated, showing no significant differences between those taking ginkgo and those on placebo on any objective or subjective measure (JAMA 2002;288:835-40).
New York University School of Medicine Professor for Alzheimer's disease Steven Ferris said the important, well-conducted clinical trial questioned previously unsubstantiated claims that ginkgo improved mental function in older people.
Last Reviewed: 26 August 2002