(levodopa and benserazide)
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Madopar tablets and capsules.
It does not contain all the available information.
It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking Madopar against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine. You may need to read it again.
What Madopar is used for
The name of your medicine is Madopar. It contains two active ingredients called levodopa and benserazide.
Madopar belongs to a group of medicines called antiparkinsonian agents and is used for the treatment of Parkinson's disease.
Antiparkinsonian agents work on the central nervous system. The symptoms of Parkinson's disease are caused by a deficiency of a natural substance in the brain called dopamine. Madopar helps to replace this substance. By improving muscle control, Madopar allows more normal movements of the body.
The symptoms of patients suffering from Parkinson's disease can be reduced by taking this medicine. Madopar does not, however, cure the disease, since the cause of the dopamine deficiency within the brain is not removed.
Your doctor, however, may have prescribed Madopar for another purpose.
Ask your doctor if you have any questions about why Madopar has been prescribed for you.
This medicine is available only with a doctor's prescription.
Before you take Madopar
Do not take Madopar if:
Do not take Madopar if you have an allergy to:
- any medicine containing levodopa or benserazide
- any of the ingredients listed at the end of this leaflet
Some of the symptoms of an allergic reaction may include:
- shortness of breath
- wheezing or difficulty breathing
- swelling of the face, lips, tongue or other parts of the body
- rash, itching or hives on the skin
Do not take Madopar if:
- you have taken a non-selective monoamine oxidase inhibitor (MAO-I) medicine such as tranylcypromine or phenelzine within the last 2 weeks
- you have taken a combination of a selective MAO-A inhibitor such as moclobemide with a selective MAO-B inhibitor such as selegiline or rasagiline
- you have untreated heart, liver, kidney, lung, blood or endocrine (hormonal) disease
- you have narrow (closed) angle glaucoma (high pressure in the eye)
- you are being treated for severe mental illness (active psychosis or serious psychoneurosis)
- you have melanoma or suspected melanoma
- you are under the age of 30
- you are being treated for Huntington's chorea or intention tremor
Do not take Madopar after the expiry date (EXP) printed on the pack or if the packaging is torn or shows signs of tampering. If you take this medicine after the expiry date has passed, it may not work as well.
If you are not sure if you should be taking Madopar, talk to your doctor.
You must tell your doctor if:
- you are allergic to any other medicines, foods, dyes or preservatives
- you have any other health problems including:
- convulsions (fits)
- stomach ulcers
- feeling down (depression) or other psychological disorders
- osteoporosis or osteomalacia
- irregular heart beat
- wide-angle glaucoma (high pressure in the eye)
- any compulsive behaviour disorder
- onset of sudden sleep disorder
- other illnesses
- you plan to have surgery
- you are pregnant or plan to become pregnant.
Madopar should not be take