Granisetron hydrochloride equivalent to Granisetron 1 mg/1 mL and 3 mg/3 mL, concentrated solution for injection
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Granisetron-AFT.
It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you having this medicine against the benefits they expect it will provide.
If you have any concerns about this medicine, ask your doctor or pharmacist. Keep this leaflet with the medicine. You may need to read it again.
What Granisetron-AFT is used for
Granisetron-AFT contains the active ingredient granisetron. Granisetron belongs to a group of medicines called anti-emetics.
Granisetron-AFT is used to prevent nausea (feeling sick) and vomiting. It is especially useful when you need to have medical treatment that may cause you to feel or be sick, for example, chemotherapy or radiotherapy.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason.
Granisetron-AFT is only available with a doctor's prescription. It is not addictive.
Before you are given Granisetron-AFT
When you must not be given it
You must not be given Granisetron-AFT if you have ever had an allergy to:
- granisetron (the active ingredient in Granisetron-AFT)
- any of the other ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
If you are unsure if you should be given Granisetron-AFT, talk to your doctor.
Before you are given it
Tell your doctor if you have any of the following health problems / medical conditions:
- if you have allergies to any other medicines, foods, dyes or preservatives.
- you have severe constipation.
- you are pregnant or plan to become pregnant or are breast-feeding. Your doctor can discuss with you the risks and benefits of using Granisetron-AFT while you are pregnant or breast-feeding.
- you have been given granisetron before, and you became unwell. You may need to be given another medicine instead.
- you have a heart condition related to changes in the rhythm or rate of your heart beat.
If you have not told your doctor about any of the above, tell him/her before you are given Granisetron-AFT.
Taking other medicines
Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Some medicines and Granisetron-AFT may interfere with each other. These include:
- Phenobarbitone – a medicine used to treat epilepsy.
Phenobarbitone may be affected by Granisetron-AFT or may affect how well Granisetron-AFT works. You may need different amounts of your medicine, or you may need to take a different medicine.
Your doctor and pharmacist have more information on medicines to be careful of or avoid while being given Granisetron-AFT.
If you have not told your doctor about any of these things, tell him/her before you are given this medicine.
How Granisetron-AFT is given
How much is given
Granisetron-AFT will only be given by a doctor or nurse. Your doctor will decide what dose and how long you will receive Granisetron-AFT. This depends on your condition and other factors such as your weight.
How it is given
Granistron-AFT is given as a fast or slow injection into a vein (intravenous 'drip'). It must only be given by a nurse or doctor.
If you take too much (overdose)
Because Granisetron-AFT will be given in hospital by a doctor or nurse it is unlikely that you will be given too large a dose. However, if you experience severe side effects tell your doctor immediately.
Symptoms of an overdose may include the side effects listed below in the 'Side Effects' section but are usually of a more severe nature. Ask your doctor or pharmacist if you have any concerns.
While you are being given Granisetron-AFT
Things you must do
Tell any other doctors, dentists, and pharmacists who treat you that you are being given Granisetron-AFT.
Tell your doctor immediately if you become pregnant while you are being treated with Granisetron-AFT.
Keep all of your doctor's appointments so that your progress can be checked.
Things you must not do
Do not take any other medicines whether they require a prescription or not without first telling your doctor.
Things to be careful of
Be careful driving, operating machinery or doing jobs that require you to be alert until you know how Granisetron-AFT affects you.
Be careful when drinking alcohol while you are being given this medicine. If you drink alcohol, dizziness or light-headedness may be worse.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are being given Granisetron-AFT. This medicine helps most people with nausea and vomiting, but it may have unwanted side effects in a few people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.
Do not be alarmed by the following lists of side effects. You may not experience any of them.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
- unusual tiredness or weakness
- dizziness or light-headedness
- difficulty in sleeping
- abdominal pain
- altered taste
- skin rash
The above list includes the more common side effects of your medicine.
If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital:
- chest pain
- changes in your heart beat
- severe dizziness or fainting
- symptoms of an allergic reaction, such as shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
The above list includes very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are rare.
Tell your doctor or pharmacist if you notice anything else that is making you feel unwell. Some people may have other side effects not yet known or mentioned in this leaflet.
Granisetron-AFT will be stored in the pharmacy or on the ward. The solution for injection should be kept in a cool place, protected from light where the temperature stays below 30°C.
What it looks like
Granisetron-AFT ampoules are 1 mL and 3 mL glass ampoules containing a clear, colourless or faintly yellow-brown solution. It is supplied in packs of 1 or 5 ampoules.
Granisetron-AFT ampoules contain 1 mg/1 mL or 3 mg/3 mL of the active ingredient granisetron. They also contain:
- citric acid monohydrate
- sodium chloride
- sodium citrate dihydrate
- water for injections
AFT Pharmaceuticals Pty Ltd
113 Wicks Road
Australian Registration Numbers:
mL: AUST R 300321.
3 mg/3 mL: AUST R 300322.
This leaflet was prepared on: 31 May 2018.
Published by MIMS August 2018