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contains the active ingredient ramipril
Consumer Medicine Information
This leaflet answers some common questions about Tryzan Tabs.
It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the risks of you taking Tryzan Tabs against the benefits expected for you.
If you have any concerns about taking this medicine, talk to your doctor or pharmacist.
Keep this leaflet with your medicine. You may need to read it again.
Tryzan Tabs are used to treat:
Tryzan Tabs are also used to reduce the risk of cardiovascular problems and complications in patients aged 55 years or more with heart or blood vessel disease, or diabetes.
Tryzan Tabs belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors.
It works by widening the blood vessels, which reduces the pressure in the vessels, making it easier for your heart to pump blood around your body. This helps increase the supply of oxygen to your heart, so that when you place extra demands on your heart, such as during exercise, your heart may cope better and you may not get short of breath as easily.
By increasing the supply of oxygen to your heart, your heart does not have to work as hard and it is under less stress, which may reduce the risk of further damage occurring to it following a heart attack.
Tryzan Tabs also improve blood flow through the small blood vessels found in the kidneys, which helps the kidneys to work more efficiently. This in turn can help to slow down the progression of kidney damage that might result from having diabetes or high blood pressure.
Ask your doctor if you have any questions about why Tryzan Tabs have been prescribed for you. Your doctor may have prescribed Tryzan Tabs for another reason.
Tryzan Tabs are not addictive.
Tryzan Tabs are available only with a doctor's prescription.
Tryzan Tabs are not recommended for use in children. Safety and effectiveness of Tryzan Tabs in children have not been clearly established.
Do not take Tryzan Tabs if you have an allergy to:
Some of the symptoms of an allergic reaction may include:
Do not take Tryzan Tabs if you have taken any other ACE inhibitor medicine before, which caused your face, lips, tongue, throat, hands or feet to swell up, or made it hard for you to breathe. If you have had an allergic reaction to an ACE inhibitor before, you could be allergic to Tryzan Tabs.
Do not take Tryzan Tabs if you or your family have a history of swelling of the face, lips, tongue, throat, intestines, hands or feet, for no apparent reason.
Do not take Tryzan Tabs if you have or have had, any of the following medical conditions:
Do not take Tryzan Tabs if you undergo dialysis using certain high-flux membranes.
Do not take Tryzan Tabs if you are pregnant or plan to become pregnant. Tryzan Tabs may affect your developing baby if you take it during pregnancy.
Do not breastfeed if you are taking Tryzan Tabs. Tryzan Tabs may pass into breast milk and affect your baby.
Do not take Tryzan Tabs after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking Tryzan Tabs, talk to your doctor.
Tell your doctor if you have allergies to any other medicine, foods, preservatives or dyes.
Tell you doctor if you have, or have had any of the following medical conditions:
Tell your doctor if you have a family history of swelling of the face, lips, tongue, throat, intestines, hands or feet.
You must also tell your doctor if you:
If you have not told your doctor about any of the above, tell him/her before you start taking Tryzan Tabs.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop. Some medicines and Tryzan Tabs may interfere with each other. These include:
These medicines may be affected by Tryzan Tabs, or may affect how well it works. You may need to use different amounts of your medicine, or you may need to take different medicines.
Your doctor or pharmacist have more information on medicines to be careful with or avoid while taking Tryzan Tabs.
Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the pack, ask your doctor or pharmacist for help.
Your doctor or pharmacist will tell you how many tablets or capsules you will need to take each day. This depends on your condition and whether or not you are taking any other medicines.
Take Tryzan Tabs only when prescribed by your doctor. Your doctor will select a dose when they prescribe Tryzan Tabs for you. Some patients may need a lower starting dose. The usual dose of Tryzan Tabs is:
Depending on your response, your doctor may adjust the dose.
If two tablets are prescribed, your doctor may want you to take them both together or at different times. This will depend on the condition being treated and how you respond to Tryzan Tabs.
Swallow the tablets whole with a full glass of water.
Take Tryzan Tabs at about the same time each day. Taking it at the same time each day will have the best effect. It will also help you remember when to take it.
It does not matter if you take Tryzan Tabs before or after food.
Continue taking your medicine for as long as your doctor tells you. Tryzan Tabs helps control your condition, but does not cure it. Therefore you must take Tryzan Tabs every day.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for the dose you missed. This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Tryzan Tabs. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
If you take too much Tryzan Tabs, you may feel light-headed, dizzy or you may faint. You may also experience slow heart beat.
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Tryzan Tabs.
Tell any other doctors, dentists and pharmacists who treat you that you are taking Tryzan Tabs.
Make sure you drink enough water during exercise and hot weather when you are taking Tryzan Tabs, especially if you sweat a lot. If you do not drink enough water while taking Tryzan Tabs, you may feel faint, light-headed or sick. This is because your blood pressure is dropping suddenly. If you continue to feel unwell, tell your doctor.
If you have excess vomiting or diarrhoea while taking Tryzan Tabs, tell your doctor. This may cause you to lose too much water and salt and your blood pressure may drop too much.
If you feel light-headed or dizzy after taking your first dose of Tryzan Tabs or when your dose is increased, tell your doctor immediately.
If you plan to have surgery that needs a general anaesthetic, tell your doctor or dentist that you are taking Tryzan Tabs. Your blood pressure may drop suddenly.
If you become pregnant while taking Tryzan Tabs, tell your doctor immediately.
If you are about to have any blood tests, tell your doctor that you are taking Tryzan Tabs. It may interfere with the results of some tests.
Have your blood pressure checked when your doctor says, to make sure Tryzan Tabs are working.
Go to your doctor regularly for a check-up. Your doctor may occasionally do a blood test to check your potassium levels and see how your kidneys are working.
Do not stop taking Tryzan Tabs to treat any other complaints unless your doctor tells you to.
Do not give Tryzan Tabs to anyone else, even if they have the same condition as you.
Do not stop taking Tryzan Tabs, or lower or increase the dosage without checking with your doctor.
If you feel light-headed, dizzy or faint when getting out of bed or standing up, get up slowly. Standing up slowly, especially when you get up from bed or chairs, will help your body get used to the change in position and blood pressure. If this problem continues or gets worse, talk to your doctor.
Be careful driving or operating machinery until you know how Tryzan Tabs affects you. Tryzan Tabs may cause dizziness or lightheadedness, tiredness or drowsiness in some people. If you have any of these symptoms, no not drive, operate machinery or do anything else that could be dangerous.
Be careful when drinking alcohol while you are taking Tryzan Tabs. If you drink alcohol, dizziness or light-headedness may be worse.
Some self help measures suggested below may help your condition. Your doctor or pharmacist can give you more information about these measures.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Tryzan Tabs. Tryzan Tabs helps most people, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.
Do not be alarmed by this list of possible side effects. You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
The above list includes the more common side effects of Tryzan Tabs. They are usually mild.
Tell your doctor as soon as possible if you notice any of the following:
The above list includes serious side effects that may require medical attention. Serious side effects are rare.
If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital:
The above list includes very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are very rare.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell. Other side effects not listed above may also occur in some people.
Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they may not keep well.
Keep your tablets in a cool dry place where the temperature stays below 25 °C.
Do not store Tryzan Tabs or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking Tryzan Tabs, or the expiry date has passed, ask your pharmacist what to do with any tablets that are left over.
Tryzan Tabs come in four strengths of tablets:
Each pack contains 30 tablets.
The active ingredient in Tryzan Tabs is ramipril
The tablets also contain the following inactive ingredients:
Tryzan Tabs do not contain gluten.
Tryzan Tabs is supplied by:
Alphapharm Pty Limited
(ABN 002 359 739)
Chase Building 2
Wentworth Park Road
Glebe NSW 2037
Phone: (02) 9298 3999
Phone: 1800 028 365
Australian registration numbers:
Tryzan Tabs 1.25: AUST R 129873
Tryzan Tabs 2.5: AUST R 129916
Tryzan Tabs 5: AUST R 129918"
Tryzan Tabs 10: AUST R 129921
This leaflet was prepared on 16 June 2008.
Published by MIMS/myDr September 2008