contains the active ingredient metoclopramide hydrochloride
Consumer Medicine Information
This leaflet answers some common questions about Pramin.
It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the risks of you taking Pramin against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, talk to your doctor or pharmacist.
Keep this leaflet with your medicine. You may need to read it again.
In Adults over 20 years, Pramin is used to:
In young adults and children over 1 year of age this medicine is used to:
Pramin belongs to a group of medicines called anti-emetics and is thought to work by blocking the action of a chemical in the brain which causes nausea and vomiting. It also increases the muscle contractions in the stomach and small intestine.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason.
This medicine is available only with a doctor's prescription.
There is no evidence that Pramin is addictive.
Do not take Pramin if you are allergic to medicines containing metoclopramide hydrochloride or any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include skin rash, itching or hives, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath.
Do not take Pramin if you:
Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start taking this medicine, talk to your doctor.
Tell your doctor if you have allergies to any other medicines, foods, dyes or preservatives.
Tell your doctor if you are pregnant or plan to become pregnant. Your doctor will discuss the risks and benefits of taking this medicine during pregnancy.
Tell your doctor if you are breastfeeding or wish to breastfeed. Pramin passes into breast milk and can affect the flow of your breast milk. Your doctor will discuss the risks and benefits of taking this medicine when breastfeeding.
Tell your doctor if you have or have had any of the following medical conditions:
Your doctor may want to take special care if you have any of these conditions.
If you have not told your doctor about any of the above, tell him/her before you start taking Pramin.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Some medicines and Pramin may interfere with each other. These include:
These medicines may be affected by Pramin or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.
Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the pack, ask your doctor or pharmacist for help.
Your doctor may advise you to take a different dose. This depends on your condition and whether or not you are taking any other medicines.
The total daily dosage of Pramin, especially for children and young adults, should not normally exceed 0.5mg/kg bodyweight or 30mg daily.
Space the doses as evenly as possible throughout the day.
20 + years - 1 tablet every 8 hours
15 to 20 years - 1/2 to 1 tablet every 8 hours
Children and young adults are very sensitive to the effects of Pramin. Your doctor will normally start the treatment at the lower dose. Do not exceed the prescribed dose in these age groups.
Swallow the tablets with a full glass of water.
The tablets can be broken in half (along the break line)
Do not exceed the prescribed dose.
Pramin is best taken 30 minutes before symptoms are likely to occur or 30 minutes before meals. Space the doses of Pramin evenly throughout the day.
Your doctor may tell you to take Pramin only when required for each occasion of nausea or vomiting.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take the missed dose as soon as you remember, and then go back to taking your tablets as you would normally.
Do not take a double dose to make up for the dose you missed. This may increase the chance of getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
Continue taking your medicine for as long as your doctor tells you.
Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much Pramin. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
If you take too much Pramin, you may experience drowsiness, dizziness, agitation, nausea, vomiting, and unusual movements, such as trembling and shaking of the hands and feet, and uncontrolled movements of the tongue, mouth or jaw.
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Pramin.
Tell any other doctors, dentists and pharmacists who treat you that you are taking this medicine.
If your symptoms do not improve or if they become worse, tell your doctor.
If you become pregnant while taking this medicine, tell your doctor immediately.
If you plan to have surgery, including dental surgery, tell your surgeon, anaesthetist or dentist that you are taking Pramin.
If you need to have any liver function tests or other tests, tell your doctor. Pramin may affect the results of some tests.
Do not use Pramin to treat any other complaints unless your doctor tells you to.
Do not give your medicine to anyone else, even if they have the same condition as you.
Be careful driving or operating machinery until you know how Pramin affects you. Pramin may cause drowsiness, dizziness or lightheadedness in some people. If any of these occur, do not drive, operate machinery or do anything else that could be dangerous.
Be careful when drinking alcohol while taking Pramin. Combining Pramin and alcohol can make you more sleepy.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Pramin. Like all other medicines, Pramin may have unwanted side effects in some people. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
If you are over 65 years of age, you may have an increased chance of getting side effects.
Do not be alarmed by the following lists of side effects. You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
The above list includes the more common or mild side effects of Pramin.
Tell your doctor as soon as possible if you notice any of the following:
The above list includes serious side effects which may require medical attention. Serious side effects are rare.
If any of the following happen, stop taking Pramin and tell your doctor immediately, or go to Accident and Emergency at the nearest hospital:
These are rare yet serious side effects and may need urgent medical attention.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell. Other side effects not listed above may also occur in some patients.
Keep your tablets in the bottle until it is time to take them. If you take the tablets out of the bottle they may not keep well.
Keep your tablets in a cool dry place where the temperature stays below 30°C.
Do not store Pramin or any other medicine in the bathroom or near a sink. Do not leave it in the car or on a window sill. Heat and dampness can destroy some medicines.
Keep Pramin where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.
Pramin is a round white tablet marked "ME" over "10" on one side and "G" on the reverse.
Each bottle contains 25 tablets.
The active ingredient in Pramin is metoclopramide hydrochloride. Each Pramin tablet contains 10 mg of metoclopramide hydrochloride.
The tablets also contain:
The tablets are gluten free.
Pramin is made in Australia by:
Alphapharm Pty Limited
(ABN 93 002 359 739)
Level 1, 30 The Bond
30-34 Hickson Road
Millers Point NSW 2000
Phone: (02) 9298 3999
Australian Registration Number:
Pramin - Aust R 17661
This leaflet was prepared on 03 June 2015.
Published by MIMS October 2015