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perindopril (pronounced per-in-do-pril)
Consumer Medicine Information
This leaflet answers some common questions about PERINDO. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of taking PERINDO against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist. Keep this leaflet with the medicine. You may need to read it again.
The name of your medicine is PERINDO. The medicine contains the active ingredient perindopril erbumine. Perindopril belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors.
PERINDO is available only with a doctor's prescription.
PERINDO lowers high blood pressure, a condition which doctors call hypertension.
Everyone has blood pressure. This pressure helps get your blood all around the body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have high blood pressure when your blood pressure stays higher than is needed, even when you are calm or relaxed.
There are usually no symptoms of high blood pressure. The only way of knowing that you have it is to have your blood pressure checked on a regular basis. If high blood pressure is not treated it can lead to serious health problems. You may feel fine and have no symptoms, but eventually it can cause stroke, heart disease and kidney failure. PERINDO helps lower your blood pressure.
You may be prescribed PERINDO for heart failure. Heart failure means that the heart muscle cannot pump blood strongly enough to supply all the blood needed throughout the body. Heart failure is not the same as heart attack and does not mean that the heart stops working.
Some people develop heart failure after having had a heart attack. However there are also other causes of heart failure.
Heart failure may start off with no symptoms, but as the condition progresses, you may feel short of breath or may get tired easily after light physical activity such as walking. You may wake up short of breath at night. Fluid may collect in different parts of the body, often first noticed as swollen ankles and feet. In severe heart failure, symptoms may occur even at rest.
PERINDO helps to treat heart failure. If you follow your doctor's advice, your ability to perform daily activities may improve. You may breath more easily, feel less tired, and have less swelling.
You may also have been prescribed PERINDO if you have coronary artery disease. Coronary artery disease is narrowing of the vessels carrying blood to the heart. In patients with coronary artery disease, PERINDO has been shown to reduce some of the risks, including heart attacks.
There are some people who shouldn't take PERINDO. Please read the list below. If you think any of these situations apply to you or you have any questions, please consult your doctor.
If you think any of these situations apply to you, or you have any doubts or questions about taking PERINDO consult your doctor or pharmacist.
Taking PERINDO may change the effect of some medicines, and some medicines may affect how well PERINDO works. You may need different amounts of your medication or to take different medicines. The medicines that may interact with PERINDO include the following:
Medicines which may affect the blood cells, such as allopurinol, procainamide. It is a good idea to remind your doctor of all other medicines you take. Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking PERINDO.
The dose of PERINDO you may need each day will be decided and adjusted by your doctor. This will normally be 2mg (PERINDO 2MG), 4mg (PERINDO 4MG) or 8mg (PERINDO 8MG) once daily for high blood pressure and for people with coronary artery disease or 2mg (PERINDO 2MG) to 4mg (PERINDO 4MG) once daily for heart failure.
Swallow your tablet(s) with water, preferably in the morning before a meal.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking it as you would normally.
Do not take a double dose to make up for the dose that you missed.
PERINDO helps control your blood pressure, or heart failure or coronary artery disease but does not cure it. Continue taking the tablets for as long as your doctor tells you.
Taking too much PERINDO (an overdose) may cause low blood pressure (also known as hypotension). The most likely effect in case of overdose is low blood pressure which can make you feel dizzy or faint. If this happens, lying down with the legs elevated can help. Other effects like sickness, cramps, sleepiness, confusion, kidney problems, salt and water disturbances are possible. You may require urgent medical attention.
If you think that you or anyone else may have taken too much PERINDO then act immediately:
Take PERINDO exactly as your doctor has prescribed. Otherwise you may not get the benefits from treatment. Tell all doctors, dentists and pharmacists who are involved with your treatment that you are taking PERINDO.
Make sure you drink enough water during exercise and hot weather especially if you sweat a lot. This will help you avoid any dizziness or light-headedness caused by a sudden drop in blood pressure.
Tell your doctor straight away if you have excessive vomiting or diarrhoea while taking PERINDO.
Take care when driving or operating machinery until you know how PERINDO affects you.
Dizziness or weakness due to low blood pressure may occur in certain patients. If you have any of these symptoms do not drive or operate machinery.
If you do not feel well while you are taking PERINDO then tell your doctor or pharmacist as soon as possible. All medicines can have side effects. Sometimes they are serious, most of the time they are not.
PERINDO helps most people with high blood pressure, heart failure or coronary artery disease, but it may have unwanted side effects in a few people. These side effects when they occur are usually mild:
With PERINDO, the side effects can include:
Consult your doctor or pharmacist if you experience any of these or notice anything else that is making you feel unwell. Do not be alarmed by this list of possible side effects. You may not experience any of them. Other uncommon side effects have been reported and you should ask your doctor or pharmacist if you want to know more.
If any of the signs below occur then tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital. These side effects are extremely rare but can become serious:
Heat and dampness can destroy some medicines. Keep your tablets in the pack until it is time to take them. Keep them in a cool, dry place where it stays below 30°C. Do not store medicines in a bathroom or near a sink. Do not leave them in a car or on a windowsill. Keep them where children cannot reach them. Keep the container tightly closed.
If your doctor tells you to stop taking PERINDO, or the tablets have passed their expiry date, return any leftover tablets to your pharmacist for disposal.
PERINDO 2MG, PERINDO 4MG and PERINDO 8MG are contained in a blister strip that is itself enclosed in an aluminium foil envelope containing a desiccant sachet. Each box contains 30 tablets. A desiccant is a substance that absorbs moisture and helps to protect the tablets, especially when it is very humid.
The inactive ingredients include microcrystalline cellulose, lactose, magnesium stearate, colloidal anhydrous silica, and (8mg tablet only) aluminium copper complexes of chlorophyllins (E141ii) lake.
PERINDO is registered on the Australian register of Therapeutic Goods.
Australian Register Number:
PERINDO 2MG tablets: AUST R 121747
PERINDO 4MG tablets: AUST R 121748
PERINDO 8MG tablets: AUST R 121749
PERINDO is distributed in Australia by:
Alphapharm Pty Limited
Level 1, 30 The Bond
30-34 Hickson Road
Millers Point NSW 2000
ABN 93 002 359 739
This document was last revised in April 2013
Published by MIMS July 2013
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