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Consumer Medicine Information
This leaflet answers some common questions about Panafcort. It does not contain all the information that is known about Panafcort.
It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking Panafcort against the benefits they expect it will have for you.
If you have any concerns about taking this medicine ask your doctor or pharmacist.
Keep this leaflet with the medicine. You may need to read it again.
Panafcort contains prednisone as the active ingredient. Prednisone belongs to a group of medicines called corticosteroids which are a synthetic version of a naturally occurring body hormone called cortisol.
Panafcort is used in the treatment of many different conditions. Some of these conditions include: severe allergies, severe or chronic asthma, skin problems, arthritis, inflammatory diseases of the bowel, cancer and "auto-immune" diseases.
It is also used to prevent or reduce the symptoms of inflammation (such as swelling, redness, pain, tenderness or itching) in any part of the body. These symptoms can occur in response to injury or can be caused by many different conditions.
Panafcort works by entering inflammatory cells and blocking the inflammatory reaction. It is only able to prevent or reduce symptoms of your condition, it does not cure it.
Ask your doctor if you have any questions about why Panafcort has been prescribed for you.
Your doctor may have prescribed it for another purpose.
This medicine is only available with a doctor's prescription.
There is no evidence that it is addictive.
Do not take Panafcort if you have ever had an allergic reaction to:
Symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty in breathing; swelling of the face, lips, tongue or any other parts of the body; rash, itching or hives on the skin.
Do not take it if you have a current serious or uncontrolled infection, including fungal infections.
Do not take Panafcort after the expiry date (EXP) printed on the bottle.
It may have no effect at all or an entirely unexpected effect if you take it after the expiry date.
Do not take it if the bottle shows signs of having been tampered with.
Do not take this medicine to treat any other complaints unless your doctor has instructed you to do so.
Do not give this medicine to anyone else.
Tell your doctor if you are allergic to any other medicines or any foods, dyes or preservatives.
Tell your doctor if you have or have had any of the following medical conditions:
Do not take Panafcort if you are pregnant or plan to become pregnant unless you and your doctor have discussed the risks and benefits involved.
Do not take it if you are breast feeding or plan to breast feed.
It is not recommended for use while breastfeeding as it is found in breast milk.
If you have not told your doctor about any of these things, tell them before you take Panafcort.
Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from a pharmacy, supermarket or health food shop.
Some medicines may interfere with Panafcort. These include:
These medicines may be affected by Panafcort or may affect how well it works. You may need to take different amounts of your medicine or you may need to take different medicines. Your doctor or pharmacist has a more complete list of medicines to avoid while taking Panafcort.
Take special care when giving Panafcort to children. It should only be given under your doctor's supervision.
If possible, children should not be exposed to common childhood illnesses such as chickenpox or measles while they are taking Panafcort. They may suffer from more serious attacks of these illnesses if such exposure occurs.
Children should not be vaccinated with "live" vaccines against common childhood illnesses while they are taking Panafcort, as this may result in severe attacks of these illnesses.
Potentially serious side effects can occur in children and growing teenagers who are taking corticosteroids. Some of these include obesity, slowed growth, osteoporosis (softening of the bone), and changes to the adrenal glands.
Elderly patients may be more sensitive to the effects or side effects of this medicine.
Your doctor will tell you how much Panafcort to take.
The dose will depend on the condition being treated and your response to the treatment. Your initial dose will be maintained or adjusted until a satisfactory response is noted.
Swallow the tablet whole with a glass of water.
Panafcort is best taken with or immediately after food.
How often this medicine can be taken may vary depending on what condition is being treated. It can be taken once daily, several times a day or on alternate days (every other day).
If you take it once a day or every second day, then it is best taken at breakfast time. If it needs to be taken more than once a day, then space it out during the day.
Continue taking Panafcort for as long as your doctor tells you.
This will depend on your condition and on your response to treatment. Some people will need this medicine for only short periods of time, whilst others may require long term therapy.
Do not miss any doses and do not stop taking the medicine even if you feel better.
Missing doses may make your symptoms worse.
Individuals will vary greatly in their response to Panafcort. Your doctor will check your progress at regular intervals.
If you miss a dose of this medicine the decision of whether you should take it or not will depend on how many times a day you take Panafcort.
If you are taking Panafcort:
If you miss a dose and remember in less than 12 hours, take it straight away, then continue as normal the next day. Otherwise, skip that day's dose but be sure to take the next day's dose when it is due.
If you miss a dose and it is more than 2 hours before your next dose is due, take it straight away, then continue as you normally would.
If it is less than 2 hours to your next dose, skip the dose you have missed but be sure to take the next dose when you are meant to.
If you miss a dose and remember it the same morning, take it straight away, then continue as you normally would. If you do not remember the missed dose until later, wait and take it the following morning. Then skip a day before continuing your regular dosage schedule.
Do not try to make up for missed doses by taking more than one dose at a time.
If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.
Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at your nearest hospital if you think that you or anyone else may have taken too much Panafcort. Do this even if there are no signs of discomfort or poisoning.
You may need urgent medical attention.
Take Panafcort exactly as your doctor has prescribed.
If you do not follow your doctor's instructions, you may not get improvement in the symptoms of your condition. Try not to miss any doses and take the medicine even if you feel well.
Tell your doctor if your condition returns or becomes worse after your dose of Panafcort has been reduced or treatment has been stopped.
Tell your doctor immediately if you become pregnant while taking Panafcort.
Tell any other doctors, dentists and pharmacists who are treating you that you are taking Panafcort, especially if you are being started on any new medicines.
Tell your doctor, surgeon or dentist that you are taking Panafcort if you are about to undergo surgery or an operation.
Your dose of this medicine may need to be increased to cover you during the stress of the operation.
Tell your doctor straight away if you are a diabetic, and you notice a change in the results of your blood or urine sugar tests.
This medicine may affect your blood sugar levels as it can affect the body's ability to handle glucose. For diabetics, this means that your diabetes may become more severe. For others, diabetes may develop for the first time while taking corticosteroids such as Panafcort.
Ask your doctor, when and how you should stop taking Panafcort.
If you have been taking it for a long time your doctor may gradually reduce the amount you are taking over a period of several days, weeks or months before stopping completely.
If you have been taking Panafcort for a short period of time, this may not apply.
Do not give this medicine to anyone else even if their symptoms seem similar to yours.
Do not stop taking Panafcort suddenly unless advised by your doctor.
If you stop taking it suddenly, the symptoms of your condition may return or you may develop symptoms of cortisol deficiency such as fainting, weakness, restlessness, nausea, vomiting, headache, dizziness, muscle weakness or joint pain.
Do not have any immunisations (particularly with "live" vaccines such as measles, oral polio or yellow fever) without your doctor's approval while you are being treated with Panafcort.
Avoid close contact with anyone who has a contagious disease such as measles or chickenpox.
Exposure to such diseases while you are taking this medicine, particularly if large doses are being taken, can put you at greater risk of developing these diseases if you have not had them before.
Tell your doctor straight away if you think you have been exposed to chickenpox or measles.
As with any new medicine, you should take care when driving or operating machinery until you know how Panafcort affects you.
Check with your doctor or pharmacist before drinking alcohol while you are taking Panafcort.
If you drink alcohol while taking it you may find that stomach problems occur.
The signs and symptoms of infections such as fever or inflammation may be hidden by the anti-inflammatory action of Panafcort. You should see your doctor for medical advice for any but the most minor infections.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Panafcort.
Panafcort helps most people who take it, but it may have unwanted side effects in some people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have.
When Panafcort is taken for short periods of time it is unlikely to cause any problems.
Tell your doctor if you notice any of the following side effects and they worry you:
When Panafcort is taken for long periods of time and in high doses the risk of side effects is greater.
Tell your doctor if you notice any of the following and they worry you:
- bloating and rounding of the face (moon face)
- weight gain
- redistribution of body fat
- water retention leading to swollen legs and feet, high blood pressure or an irregular heart beat
- cramps or weakness in the muscles of the arms and legs
- slowed growth in children
- irregular menstrual periods.
- red or flushed face
- extra hair growth
- red or purple streaks
- easy bruising
- skin thinning
- increased sweating
- poor wound healing.
- an increased seriousness or frequency of infections.
- excessive mood swings (such as changes in personality)
- anxiety or nervousness
- trouble sleeping.
- decreased or blurred vision
- eyes sticking out too far
Tell your doctor immediately or go to Accident and Emergency at your nearest hospital if you notice any of the following symptoms:
These are all serious side effects of Panafcort. You may need urgent medical attention or hospitalisation.
Some side effects can only be detected by your doctor. So it is important to visit your doctor for regular check-ups when Panafcort is taken for long periods of time.
Such side effects can include:
Tell your doctor if you notice anything else that is making you feel unwell.
Some people may get other side effects while using Panafcort.
Do not be alarmed by this list of possible side effects. You may not experience any of them.
Keep Panafcort tablets in a cool dry place, protected from light, where the temperature stays below 30 degrees Celsius.
Do not store it or any other medicine in the bathroom or near a sink or stove. Do not leave it in the car on hot days.
Heat and dampness can destroy some medicines.
Keep it where young children cannot reach it.
A locked cupboard at least one-and-a-half metres above ground is a good place to store medicines.
Dispose of the tablets where children cannot reach them.
If your doctor tells you to stop taking Panafcort or you find that the expiry date has passed, ask your pharmacist what to do with any tablets you may have left.
Panafcort tablets are available in three strengths: 1 mg, 5 mg and 25 mg.
The 1 mg tablets are white, scored, round and biconvex. They are marked with "PN/1" on one side. Available in bottles of 100.
The 5 mg tablets are white, scored, round and biconvex. They are marked with "PN/5" on one side. Available in bottles of 60.
The 25 mg tablets are white, scored, round and biconvex. They are marked with "PN/25" on one side. Available in bottles of 30.
Panafcort 1 mg - 1 mg prednisone per tablet
Panafcort 5 mg - 5 mg prednisone per tablet
Panafcort 25 mg - 25 mg prednisone per tablet.
Panafcort tablets do not contain gluten, sucrose, tartrazine or any other azo dyes.
Aspen Pharmacare Australia Pty Ltd
34-36 Chandos St
St Leonards NSW 2065
Australian Registration Numbers:
1 mg- AUST R 39879
5 mg- AUST R 27974
25 mg- AUST R 27957
This leaflet was prepared in February 2010.
Published by MIMS/myDr May 2010