Consumer Medicine Information
This leaflet answers some common questions about NIDEM.
It does not contain all of the available information. It does not take the place of talking to your doctor, pharmacist or diabetes educator.
All medicines have benefits and risks. Your doctor has weighed the risks of you taking NIDEM against the benefits they expect it will have for you.
Talk to your doctor, pharmacist or diabetes educator if you have any concerns about taking this medicine.
Keep this leaflet with your medicine. You may need to read it again.
NIDEM is used to control blood glucose in people with Type 2 diabetes mellitus. This type of diabetes is also called non-insulin dependent diabetes mellitus (NIDDM) or maturity onset diabetes.
NIDEM is used when diet and exercise are not enough to control your blood glucose levels. It can be used alone, or in combination with other medicines for treating diabetes.
NIDEM is available only with a doctor's prescription.
NIDEM belongs to a group of medicines called sulphonylureas. These medicines lower blood
glucose by increasing the amount of insulin produced by your pancreas.
If your blood glucose is not properly controlled, you may experience hypoglycaemia (low blood glucose) or hyperglycaemia (high blood glucose).
Hypoglycaemia (low blood glucose) can occur suddenly. Signs may include:
If not treated promptly, these may progress to:
Hyperglycaemia (high blood glucose) usually occurs more slowly than hypoglycaemia. Signs of hyperglycaemia may include:
Long-term hyperglycaemia can lead to serious health problems such as heart disease, blindness, poor blood circulation, gangrene and kidney damage.
Do not take this medicine if you are allergic to:
Do not take it if you have any of the following medical conditions:
Do not take it if you are pregnant or plan to become pregnant. Insulin is more suitable for controlling blood glucose during pregnancy. Your doctor will replace NIDEM with insulin while you are pregnant.
Do not take it if you are breastfeeding. This medicine can pass into breast milk and may harm your baby.
Do not take it if the expiry date (Exp.) printed on the pack has passed.
Do not take it if the packaging shows signs of tampering or the tablets do not look quite right.
If you are not sure whether you should start taking NIDEM, ask your doctor.
Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.
Tell your doctor if you have any medical conditions, especially the following:
Tell your doctor if you
Alcohol, diet, exercise and your general health all strongly affect the control of your diabetes.
Discuss these with your doctor.
If you have not told your doctor about any of the above, tell them before you start taking NIDEM.
Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.
Some medicines may be affected by NIDEM or may affect how well it works. These include:
symptoms of inflammation, including arthritis
Your doctor or pharmacist can tell you what to do if you are taking any of these medicines. They also have more information on medicines to be careful with or avoid while taking NIDEM.
Check with your doctor or pharmacist if you are not sure whether you are taking any of these medicines.
The dose varies from patient to patient. Your doctor will decide the right dose for you.
The usual starting dose for adults is half an 80 mg tablet each day.
Your doctor may increase this dose up to four tablets a day, depending on your blood glucose levels.
Swallow the tablets with a glass of water.
This medicine can be taken before, during or after food.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take the missed dose as soon as you remember (with food), and then go back to taking your tablets as you would normally.
Do not take a double dose to make up for the dose you missed.
If you are not sure what to do, ask your doctor or pharmacist.
Keep taking NIDEM for as long as your doctor recommends. This medicine will help control diabetes but will not cure it. Most people will need to take NIDEM for long periods of time.
Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much NIDEM. Do this even if there are no signs of discomfort or poisoning.
If you take too much medicine, you may experience symptoms of hypoglycaemia (low blood glucose).
If you do experience any signs of hypoglycaemia, raise your blood glucose quickly by eating jelly beans, sugar or honey, drinking non-diet soft drink or taking glucose tablets.
Before starting any new medicine, tell your doctor or pharmacist that you are taking NIDEM.
Tell all the doctors, dentists and pharmacists who are treating you that you are taking NIDEM.
If you become pregnant while taking this medicine, tell your doctor immediately.
Make sure that you, your friends, family and work colleagues can recognise the symptoms of hypoglycaemia and hyperglycaemia and know how to treat them.
If you experience any of the symptoms of hypoglycaemia, you need to raise your blood glucose immediately. You can do this by doing one of the following:
Unless you are within 10 to 15 minutes of your next meal or snack, follow up with extra carbohydrates such as plain biscuits, fruit or milk. Taking this extra carbohydrate will prevent a second drop in your blood glucose level.
If you experience any of the signs of hyperglycaemia, contact your doctor immediately.
The risk of hyperglycaemia is increased in the following situations:
Tell your doctor if any of the following happen:
Your blood glucose may become difficult to control at these times.
Your doctor may decide to replace NIDEM with insulin
Visit your doctor regularly for check ups. Your doctor may want to check your kidneys, liver, heart and blood while you are taking this medicine.
Make sure you check your blood glucose levels regularly. This is the best way to tell if your diabetes is being controlled properly. Your doctor or diabetes educator will show you how and when to do this.
Carefully follow your doctor's and dietician’s advice on diet, drinking alcohol and exercise. If you drink alcohol while taking this medicine, you may get flushing, headache, breathing difficulties, rapid heart beat, stomach pains or feel sick and vomit. The combination of alcohol and NIDEM also increases the risk of hypoglycaemia occurring.
Tell your doctor immediately if you notice the return of any symptoms of hyperglycaemia you have experienced before starting NIDEM. These may include lethargy or tiredness, headache, thirst, passing large amounts of urine and blurred vision. These may be signs that this medicine is no longer working, even though you may have been taking it successfully for some time.
Do not skip meals while taking NIDEM.
Do not stop taking it or change the dose without checking with your doctor.
Do not give it to anyone else, even if they have the same condition as you.
Be careful driving or operating machinery until you know how this medicine affects you. NIDEM may cause dizziness in some people. Drinking alcohol can make this worse. If either of these occur, do not drive, operate machinery or do anything else that could be dangerous.
Be careful not to let your blood glucose levels fall too low. Low blood glucose levels may slow your reaction time and affect your ability to drive or operate machinery.
If you become sick with a cold, fever or flu, it is very important to continue taking NIDEM and eating your normal meals.If you have trouble eating solid food, use sugar-sweetened drinks as a carbohydrate substitute or eat small amounts of bland food. Your diabetes educator or dietician can give you a list of foods to eat on sick days.
When you are travelling, it is a good idea to:
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking NIDEM. NIDEM helps most people with diabetes but it may have unwanted side effects in some people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have.
Do not be alarmed by this list of possible side effects. You may not experience any of them.
Tell your doctor if you notice any of the following and they worry you:
Tell your doctor immediately if you notice any of the following symptoms:
Other side effects not listed above may also occur in some people. Tell your doctor if you notice anything that is making you feel unwell.
Keep your medicine where children cannot reach it. A locked cupboard at least one-and- a-half metres above the ground is a good place to store medicines.
Keep your tablets in a cool dry place where the temperature stays below 30°C.
Do not store NIDEM or any other medicine in the bathroom or near a sink.
Do not leave it in the car or on window sills. Heat and dampness can destroy some medicines.
If your doctor tells you to stop taking NIDEM, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.
NIDEM is a white to off white round, bevel-edged, uncoated tablet with cross score (+) on one face and plain on the other.
Each pack contains 100 tablets.
The active ingredient in NIDEM is gliclazide. Each NIDEM tablet contains 80 mg of gliclazide.
The tablets also contain:
The tablets do not contain gluten, sucrose, tartrazine or any other azo dyes.
Aspen Pharma Pty Ltd
34-36 Chandos Street
St Leonards NSW 2065
Australian registration number:
NIDEM - AUST R 79023
This leaflet was revised in April 2013
Published by MIMS December 2013