Select from our A to Z index of CMI (Consumer Medicines Information) leaflets for both prescription and over-the-counter medicines. Available as HTML, PDF and large font PDF.
Perindopril/amlodipine [pronounced per-in-do-pril/ am-load-i-peen]
Consumer Medicine Information
This leaflet answers some common questions about COVERAM.
It does not contain all the available information about this medicine.
Reading this leaflet does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking COVERAM against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine. You may need to read it again.
The name of your medicine is COVERAM.
The medicine contains the active ingredient perindopril arginine. Perindopril belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors.
It also contains the active ingredient amlodipine besylate. Amlodipine belongs to a group of medicines called calcium channel blockers.
Calcium channel blockers do not change the amount of calcium in your blood or bones.
COVERAM has been prescribed for you by your doctor to replace the separate tablets of perindopril and amlodipine you were taking.
One COVERAM tablet replaces separate tablets of perindopril and amlodipine.
You have been prescribed COVERAM if you have high blood pressure, also known as hypertension.
Everyone has blood pressure. This pressure helps get your blood all around the body. Your blood pressure may be different at different times of the day, depending on how busy or stressed you are.
You have high blood pressure when your blood pressure stays higher than is needed, even when you are calm or relaxed.
There are usually no symptoms of high blood pressure. The only way of knowing that you have it is to have your blood pressure checked on a regular basis. If high blood pressure is not treated it can lead to serious health problems. You may feel fine and have no symptoms, but eventually it can cause stroke, heart disease and kidney failure.
The active ingredients in COVERAM, perindopril arginine and amlodipine help lower your blood pressure.
You may also have been prescribed COVERAM if you have coronary heart disease.
Coronary heart disease is narrowing of the vessels carrying blood to the heart.
In patients with coronary artery disease, COVERAM has been shown to reduce some of the risks, including heart attacks.
COVERAM works by widening your blood vessels, which reduces pressure in the vessel, making it easier for your heart to pump blood around your body
This helps increase the supply of oxygen to your heart, so that when you place extra demands on your heart, such as during exercise, your heart may cope better and you may not get short of breath as easily.
Ask your doctor if you have any questions about why COVERAM has been prescribed for you. COVERAM is available only with a doctor's prescription.
There is no evidence that COVERAM is addictive.
There are some people who shouldn't take COVERAM. Please read the list below.
If you think any of these situations apply to you or you have any questions, please consult your doctor or pharmacist.
If you think any of these situations apply to you, or you have any doubts or questions about taking COVERAM speak to your doctor or pharmacist.
COVERAM can generally be used safely by elderly people.
Reduced kidney function is often found in elderly people and in this case, the starting dose should always be 2.5mg of perindopril arginine and 2.5mg of amlodipine taken as separate tablets.
COVERAM is not recommended for children
If you think any of these situations apply to you, or you have any doubts or questions about taking COVERAM consult your doctor or pharmacist.
Tell your doctor, pharmacist if you are taking any other medicines, including medicines you buy without a prescription from a pharmacy, supermarket or health food shop. Taking COVERAM may change the effect of some medicines, and some medicines may affect how well COVERAM works. You may need different amounts of your medication or to take different medicines.
The medicines that may interact with COVERAM include the following:
It is a good idea to remind your doctor of all other medicines you take. Your doctor or pharmacist has more information on medicines to be careful with or avoid while taking COVERAM.
Follow all directions given to you by your doctor and pharmacist carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the label, ask your doctor or pharmacist for help.
Your doctor will select a dose when they prescribe COVERAM for you. The usual dose is one tablet once daily.
Swallow your tablet(s) with a glass of water.
Take COVERAM at about the same time each day unless your doctor tells you otherwise.
Taking your tablet at the same time each day will have the best effect. It will also help you remember when to take the tablets.
COVERAM should be taken in the morning before a meal.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking it as you would normally.
Do not take a double dose to make up for the dose that you missed.
COVERAM helps control your blood pressure and/or treat your coronary heart disease but does not cure it. Continue taking the tablets for as long as your doctor tells you.
Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26 in Australia) if you think you or anyone else may have taken too much COVERAM. Do this even if there are no signs of discomfort or poisoning.
If you become pregnant while you are taking COVERAM, tell your doctor.
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking COVERAM.
Tell all doctors, dentists and pharmacists involved with your treatment that you are taking COVERAM.
Take COVERAM exactly as your doctor has prescribed. Otherwise you may not get the benefits from treatment.
If any of the signs below occur then tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital.
These side effects are extremely rare but can become serious.
If you have stopped treatment with COVERAM due to an allergic reaction you should not start taking COVERAM again.
Some self-help measures suggested below may help your condition. Talk to your doctor or pharmacist about these measures and for more information.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking COVERAM. COVERAM helps most people with high blood pressure and/or coronary heart disease, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not.
Ask your doctor or pharmacist to answer any questions you may have. Following is a list of possible side effects. Do not be alarmed by this list. You may not experience any of them.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
These side effects, when they occur are usually mild. Speak to your doctor or pharmacist if you experience any of these or notice anything else that is making you fell unwell.
If any of the signs below occur then tell your doctor immediately or go to the Accident and Emergency department at your nearest hospital:
These side effects are extremely rare but can become serious.
Keep your COVERAM tablets in the bottle until it is time to take them. COVERAM will not keep as well outside its packaging.
Keep your COVERAM tablets in a cool, dry place away from light where the temperature stays below 25°C.
Do not store medicines in a bathroom or near a sink. Do not leave them in a car or on a windowsill. Heat and dampness can destroy some medicines.
Keep your COVERAM tablets where children cannot reach them. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking COVERAM, or the tablets have passed their expiry date, return any leftover tablets to your pharmacist for disposal.
Thirty (30) tablets are supplied in a white bottle containing desiccant sachets/canisters and equipped with a white child-resistant screw-on cap.
All tablet doses include the inactive ingredients; lactose monohydrate, cellulose microcrystalline, silica colloidal anhydrous, magnesium stearate.
COVERAM is registered on the Australian register of Therapeutic Goods.
COVERAM is a product discovered by Servier Research International.
It is distributed in Australia by:
Servier Laboratories (Aust) Pty Ltd
8 Cato Street
Hawthorn Victoria 3122
ABN: 54 004 838 500
This document was last revised in February 2013.
Published by MIMS April 2013
You are under optimum weight for your height. Being underweight can carry health risks for both men and women. Check with your doctor or dietitian to find out if your current weight is healthy for you.
You have a healthy weight for your height.
You are over optimum weight for your height. You may be facing health problems, so losing some weight would be a good idea.
You are over optimum weight for your height. You may be facing health risks, so see your doctor to help you achieve a healthier weight.