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Consumer Medicine Information
This leaflet answers some common questions about Chlorsig.
It does not contain all of the available information.
It does not take the place of talking to your doctor, pharmacist or optometrist.
All medicines have risks and benefits. Your doctor, pharmacist or optometrist has weighed the risks of you taking Chlorsig against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor, pharmacist or optometrist.
Keep this leaflet with the medicine. You may need to read it again.
Chlorsig contains chloramphenicol, a synthetic antibiotic, as the active ingredient.
Chlorsig is available as eye drops and eye ointment, for external use only.
It is used to treat an eye infection called bacterial conjunctivitis, which is a bacterial infection involving the mucous membrane of the surface of the eye.
The most common symptom is the presence of a sticky yellow-white discharge with mucus and pus (or glued eyes, especially in the morning on waking). Other symptoms include a gritty sensation in the eye, redness, irritation and watering of the eyes. The infection usually starts in one eye and then spreads to the other.
Ask your doctor, pharmacist or optometrist if you have any questions about why Chlorsig has been prescribed for you. They may have prescribed it for another purpose.
Do not use Chlorsig if you are allergic to chloramphenicol or any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction to Chlorsig may include irritation, pain and swelling in the eye. Skin rashes, blisters and fever may also occur.
Do not give Chlorsig to children under 2 years of age unless your doctor or optometrist tells you.
Do not use Chlorsig after the expiry date (EXP.) printed on the pack.
Do not use Chlorsig if the packaging is torn, broken or shows signs of tampering.
Tell your doctor if the following conditions apply to you:
If you have bought this medicine without a prescription and without prior consultation from a doctor or optometrist, it is important to check the following list. Speak to your doctor or optometrist if any apply before you start to use Chlorsig:
If you have not told your doctor or optometrist about any of the above, tell them before you use Chlorsig.
Tell your doctor, optometrist or pharmacist if you are using any other medicines, including medicines that you buy without a prescription from a pharmacy, supermarket or health food shop. Some medicines may interfere with Chlorsig. These include other eye drops and eye ointments.
These medicines may reduce or increase the effectiveness of Chlorsig, reduce its own effectiveness and/or react with Chlorsig resulting in untoward or sometimes dangerous side effects.
Your doctor, optometrist or pharmacist has more information on medicines to be careful with or avoid while using this medicine.
Follow all directions given to you by your doctor, optometrist or pharmacist carefully. They may differ from the information contained in this leaflet.
The dose of Chlorsig may be different for each person and their medical condition. Your doctor, optometrist or pharmacist will recommend the right dose for you.
Do not use in children under 2 years of age except on doctor’s advice. The usual recommended doses are:
Chlorsig eye drops:
For adults and children (2 years and over): Instil 1 or 2 eye drops in the affected eye(s) every two to six hours for up to 5 days or as directed by your doctor, optometrist or pharmacist.
Chlorsig eye ointment:
For adults and children (2 years and over): Apply 1.5 cm of eye ointment every three hours for up to 5 days or as directed by your doctor, optometrist or pharmacist.
If ointment is used together with drops for day and night coverage, eye ointment should be applied before bedtime while using the drops during the day.
If the condition does not get better after 2 days, seek medical advice.
Chlorsig should be used for up to 5 days or as directed by your doctor, optometrist or pharmacist.
If it is almost time for your next dose, skip the dose you missed and use your next dose when next due.
Otherwise, use it as soon as you remember, and then go back to using it as you would normally.
If you are unsure about whether to use your next dose, speak to your doctor, optometrist or pharmacist
Do not try to make up for missed doses by using more than one dose at a time. This may increase the chance of you getting an unwanted side effect.
Accidental ingestion of the drug in adults is unlikely to cause any toxicity due to the low content of antibiotic, but consult your doctor or Poison Information Centre (see below).
If the eye drops are accidentally ingested by infants or young children, immediately telephone your doctor or Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. Urgent medical attention may be needed.
Use Chlorsig exactly as directed.
Tell all doctors, dentists, optometrists and pharmacists who are treating you that you are using Chlorsig.
Tell your doctor immediately if you become pregnant while you are using Chlorsig.
Always discuss with your doctor, optometrist or pharmacist any problems or difficulties during or after using this medicine.
Tell your doctor, optometrist or pharmacist if, for any reason, you have not taken your medicine exactly as prescribed. Otherwise they may think that it was not effective and change your treatment unnecessarily.
Do not drive or operate machinery until you know how Chlorsig affects you. Chlorsig may distort your vision temporarily. Make sure you know how you react to it before you drive a car, operate machinery or do anything else that could be dangerous.
Do not use Chlorsig for a longer time than your doctor, optometrist or pharmacist has prescribed.
Do not increase the dose, without first checking with your doctor, optometrist or pharmacist.
Do not use this medicine to treat any other complaints without checking with your doctor, optometrist or pharmacist.
Do not give this medicine to anyone else, even if they have the same condition as you.
Tell your doctor, optometrist or pharmacist as soon as possible if you do not feel well while you are using Chlorsig. All medicines have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor, optometrist or pharmacist if you have any questions.
Tell your doctor, optometrist or pharmacist immediately if you notice any of the following:
If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital:
Tell your doctor, optometrist or pharmacist if you have any other problems while using Chlorsig even if you do not think the problems are connected with the medicine or are not listed in this leaflet. Other side effects may also occur in some people.
Chlorsig eye drops:
Store unopened bottles in a refrigerator, protected from light, where the temperature stays between 2-8°C. Do not freeze. After opening, store at room temperature (below 25°C).
Discard 4 weeks after opening. Protect from light.
Chlorsig eye ointment:
Store in a cool dry place, protected from light, where the temperature stays below 25°C. Discard 4 weeks after opening.
Do not store Chlorsig in a bathroom or near a sink. Do not leave it in the car or on windowsills. Heat and dampness can destroy some medicines.
Keep Chlorsig out of the reach of children. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor, optometrist or pharmacist tells you to stop using Chlorsig or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.
Chlorsig eye drops is in a plastic dropper bottle with tamper seals. It is a clear to slightly hazy, slightly viscous, colourless, odourless liquid.
Chlorsig eye ointment is a white opaque ointment in a 4 g tube with an ophthalmic cap.
Chlorsig eye drops:
chloramphenicol 5 mg/mL (0.5%)
Chlorsig eye drops contain the preservative phenylmercuric acetate (0.002% w/v).
Chlorsig eye ointment:
chloramphenicol 10 mg/g (1%)
Chlorsig eye ointment is free from preservatives.
Aspen Pharma Pty Ltd
34-36 Chandos Street
St Leonards NSW 2065
Australian Registration numbers:
Chlorsig eye drops: AUST R 19661
Chlorsig eye ointment: AUST R 19662.
This leaflet was revised in March 2012.
Published by MIMS/myDr June 2012