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Consumer Medicine Information
This leaflet answers some common questions about Champix. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking Champix against the benefits it is expected to have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine. You may need to read it again.
Champix is a medicine to help adults stop smoking. It can help to reduce craving and withdrawal symptoms that happen while you give up smoking.
People giving up smoking are often affected by nicotine withdrawal. Symptoms of nicotine withdrawal can include craving for tobacco, irritability, frustration, feeling angry, sleep problems, depressed mood, feeling anxious, difficulty in concentrating, restlessness, decreased heart rate, increased appetite or weight gain. Not everybody is affected by some or all of the symptoms of nicotine withdrawal.
Although it is not recommended that you smoke after the first one to two weeks of treatment, Champix will reduce your enjoyment of cigarettes if you do smoke while on treatment.
Champix works by blocking the effects of nicotine in your body. There are receptors for nicotine in the brain. When cigarette smoke is inhaled, nicotine attaches to these receptors. This sends a message to a different part of the brain to release a chemical called dopamine. Dopamine gives a feeling of pleasure which only lasts for a short time. The body wants to repeat this feeling reinforcing the need to keep smoking. Based on research, it is believed that Champix works by activating these receptors and blocking nicotine from attaching to them.
To find out how well Champix works, two groups of people who tried to stop smoking were included in a clinical study: one group took Champix and the other was given sugar pills. People who took Champix had a four times higher chance of quitting smoking after 12 weeks of treatment than those who did not. People in the Champix group had a three times higher chance of still being non-smokers one year after taking this medicine.
You will normally need to take Champix for 12 weeks. Your doctor may advise you to take Champix for a further 12 weeks after your first treatment. This may increase your chances of stopping in the long term.
Champix does not contain nicotine and it is not addictive.
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason.
Champix is only available with a doctor's prescription.
There is not enough information to recommend the use of this medicine in children under the age of 18 years.
Champix helps you give up smoking. Other things you need include:
Research has found that most people who try to quit are unable to give up without outside support. Your doctor and pharmacist can give you advice, support and sources of information to help ensure your attempt to stop smoking is successful. You can also get advice and support from Quitline by calling 13 7848 (13 QUIT) if you are in Australia and 0800 778 778 if you are in New Zealand. Quitline is a free confidential telephone smoking cessation information and advice service available throughout Australia and New Zealand.
A free internet based program that offers support and advice for people taking Champix is available in Australia at www.mytimetoquit.com.au and in New Zealand at www.liferewards.co.nz.
Do not take Champix if you have an allergy to:
Some of the symptoms of an allergic reaction may include:
Do not take Champix after the expiry date printed on the carton or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.
Talk to your doctor if you are not sure whether you should take this medicine.
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.
Tell your doctor if you have or have had any of the following medical conditions:
Tell your doctor if you are pregnant or plan to become pregnant or are breast-feeding.
If you have not told your doctor about any of the above, tell him/her before you start taking Champix.
Tell your doctor or pharmacist if you are taking any other medicines, including:
This includes other medicines to help you stop smoking such as:
The use of Champix in combination with other smoking cessation therapies is not recommended. The safety and benefits of taking Champix in combination with other medicines to stop smoking have not been studied.
Tell your doctor or pharmacist if you are taking any of the following:
The effects of changes in your body resulting from stopping smoking, with or without Champix, may alter the way these medicines work. In some cases, an adjustment of dose may be necessary.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.
You are more likely to stop smoking if you are motivated to stop. Your doctor and pharmacist can provide advice, support and sources of further information to help ensure your attempt to stop smoking is successful.
Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information in this leaflet.
If you do not understand the instructions on the carton, ask your doctor or pharmacist for help.
There are 2 ways to use Champix to help you quit smoking:
Start with the white 0.5 mg tablet and then increase the dose up to the light blue 1 mg tablet. Starting with a low dose helps your body get used to Champix.
If you have severe kidney disease your doctor may prescribe a different dose.
The usual dosage instructions are listed below.
Days 1 - 3
Take one white 0.5 mg tablet once a day.
Days 4 - 7
Take one white 0.5 mg tablet in the morning and one in the evening.
Weeks 2 - 4
Take one light blue 1 mg tablet in the morning and one in the evening.
Your first box of Champix will cover your first four weeks of treatment.
Visit your doctor before the end of the fourth week that you take Champix for a check-up and for a new prescription. At this appointment, your doctor will check your progress and give you a new prescription for the tablets you need to complete your treatment.
Weeks 5 - 12
Take one light blue 1 mg tablet in the morning and one in the evening.
After 12 weeks of treatment, if you have stopped smoking, your doctor may recommend another 12 weeks of treatment with Champix. This may increase your chances of stopping smoking long term. For this course, continue to take one light blue 1 mg tablet in the morning and one in the evening.
If you do not stop smoking during the first 12 weeks of treatment or if you start smoking again after treatment, you can make another attempt to stop smoking. However, before you make another attempt, you should try to understand the reasons why your attempt to stop smoking failed, so that your next attempt has a better chance of success.
Swallow the tablets whole with a full glass of water.
Take your medicine at about the same time each day. This will have the best effect and help you remember when to take it.
It does not matter if you take Champix before or after food. Some people find it helpful to take Champix with food.
Take Champix for 12 weeks or longer as advised by your doctor. Completing the full treatment with Champix will help you stay cigarette-free.
If it is less than 6 hours before your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for the dose that you missed.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints.
Immediately telephone your doctor or contact the Poisons Information Centre for advice (telephone Australia 13 11 26 or New Zealand 0800 POISON or 0800 764 766), or go to Accident and Emergency at the nearest hospital if you think that you or anyone else may have taken too much Champix. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
Take your tablets with you to hospital.
Make sure you try to stop smoking on your quit date. If you slip up and smoke, try again.
If you have existing heart or blood vessel problems, tell your doctor as soon as possible if you notice any changes in symptoms while taking Champix. Your doctor may check your blood pressure and blood glucose levels from time to time to make sure you have not developed any unwanted side effects.
It is important to keep all of your doctor's appointments so that your progress can be checked.
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Champix.
Tell any other doctors, dentists and pharmacists who treat you that you are taking this medicine.
If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. It may affect other medicines used during surgery.
If you become pregnant while taking this medicine, tell your doctor immediately.
Do not stop taking Champix until you have completed all 12 weeks, even if you have stopped smoking. It is important to keep taking Champix for the full 12 weeks.
Do not stop taking Champix or change the dosage without checking with your doctor.
Do not take Champix to treat any other complaints unless your doctor tells you to.
Do not give your medicine to anyone else, even if they are also trying to stop smoking.
Be careful driving or operating machinery until you know how Champix affects you. Champix may cause dizziness and sleepiness in some people. If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous.
Examples of strategies to help you quit include the following:
Giving up smoking with or without treatment can cause various symptoms. These could include changes of mood, sleeplessness, difficulty concentrating, decreased heart rate, increased appetite or weight gain.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are you are taking Champix. This medicine helps many people give up smoking, but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.
Do not be alarmed by the following lists of side effects. You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
You and your family or carer need to pay special attention to your mood, behaviour and thinking while you are taking Champix. Some people have reported changes in behaviour, thinking or mood when they start taking Champix. These may include depression, anxiety, agitation, feelings of aggression, mood swings, seeing, hearing or sensing things that are not there, thoughts of self-harm or self-harm. Worsening of these symptoms has also been reported in people who already had mental health problems.
It is not known whether these are related to Champix. It is known that mood changes can be due to the effects of stopping smoking, with or without treatment.
Stop taking Champix and tell your doctor immediately if you or your family/carer notice any changes in your behaviour or thinking, if you become agitated or depressed, or have thoughts of self-harm.
Tell your doctor or pharmacist if you have nausea (feel sick) while taking Champix and it worries you. In clinical studies with Champix, up to 3 in 10 people had nausea. It usually started in the first week. Most people who had nausea still felt able to keep on taking the medicine. Some people find it helpful to take Champix with food.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
These are the more common side effects of Champix. They are usually mild.
Tell your doctor as soon as possible if you notice any of the following:
This list includes serious side effects which may require medical attention.
Tell your doctor immediately or go to Accident and Emergency at your nearest hospital and stop taking Champix if you experience any of the following:
This list includes very serious side effects. If you have some of them, you may have had a serious allergic reaction to Champix. You may need urgent medical attention or hospitalisation.
Very serious side effects are rare.
Tell your doctor or pharmacist if you notice anything else that is making you feel unwell. Other side effects not listed above may also occur in some people.
Some of these side effects (for example, changes in blood pressure or blood sugar levels) can only be found when your doctor does tests to check your progress.
Keep your tablets in the pack until it is time to take them. If you take the tablets out of the pack they may not keep well.
Keep your tablets in a cool dry place where the temperature stays below 30°C.
Do not store Champix or any other medicine in the bathroom or near a sink.
Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep it where children cannot reach it. A locked cupboard at least one-and-a half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.
Champix is available in 2 strengths:
To assist with the dosing schedule the following packs are available.
In New Zealand:
Champix 0.5 mg tablets contain the equivalent of 0.5 mg of varenicline.
Champix 1 mg tablets contain the equivalent of 1 mg of varenicline.
Each tablet of Champix contains the following inactive ingredients:
Champix is gluten free.
Champix is supplied in Australia by:
Pfizer Australia Pty Ltd
ABN 50 008 422 348
38-42 Wharf Road
West Ryde NSW 2114
Toll Free Number: 1800 675 229
Champix is supplied in New Zealand by:
Pfizer New Zealand Ltd
PO Box 3998
Auckland, New Zealand.
Toll Free Number: 0800 736 363
This leaflet was prepared in June 2013.
® Registered Trademark
© Pfizer Australia Pty Ltd 2013.
Published by MIMS/myDr September 2013