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Methylprednisolone aceponate (meth'il -predd -niz-oh -lone ass-epp -on -eight)
Consumer Medicine Information
Please read this leaflet carefully before you start your treatment.
Keep this leaflet.
You may want to read it again.
This leaflet answers some common questions about using Advantan®. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you using Advantan® against the benefits it is expected to have for you.
If you have any concerns about using Advantan®, talk to your doctor or pharmacist.
The active ingredient in Advantan® belongs to the group of medicines called corticosteroids. The corticosteroid in Advantan® is suitable to put on the skin. It is therefore called a topical corticosteroid, which is sometimes shortened to topical steroid.
When Advantan® is put on the skin, it relieves the redness, swelling, itching and irritation of the skin in eczema and psoriasis.
Advantan® preparations are available only with a doctor's prescription.
Advantan® is made up as four different preparations. Each has a distinct look and feel. They are:
The most solid is the fatty ointment; the most runny is the lotion. The ointment and cream are in-between in thickness.
Each preparation is especially suitable in consistency for a particular area of skin or skin condition needing treatment. Your doctor will prescribe the preparation most suitable for you.
The Advantan® preparations are medicines and should only be used on skin affected by the conditions described below.
All four Advantan® preparations treat eczema.
Advantan® ointment, fatty ointment and cream (but NOT lotion) also treat psoriasis.
Eczema is a skin condition with redness, swelling, oozing of fluid, crusting and later scaling. It is often very itchy.
Psoriasis is a skin disorder with raised, rough, reddened areas covered with dry, fine, silvery scales.
Your doctor may have prescribed Advantan® for another reason. Discuss this with him/her.
Advantan® is not addictive. It is not expected to affect your ability to drive a car or operate machinery.
Do not use Advantan® if you have an allergy to:
Some of the symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
Do not use Advantan® if in the area of skin you are treating:
you have infection due to
Do not use Advantan® if you have acne, rosacea or perioral dermatitis.
Your doctor will identify these conditions for you.
Do not use Advantan®
If the Advantan® packaging is damaged or it is past the expiry date, return it to your pharmacist for disposal.
If you have not told your doctor about any of the above, tell him/her before you start using Advantan®.
If you are not sure whether you should start using this medicine, talk to your doctor.
Tell your doctor if you have a known allergy to Advantan® or any ingredients listed at the end of this leaflet.
Tell your doctor if you
Your doctor can discuss with you the risks and benefits of using Advantan®.
Advantan® should be used only on the skin. Avoid getting Advantan® in your eyes. Do not put Advantan® in your mouth. Do not swallow Advantan®.
Tell your doctor or pharmacist if you are on any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while using Advantan®.
Follow carefully all directions given to you by your doctor or pharmacist.
They may differ from the information contained in this leaflet.
If you do not understand the instructions in this leaflet, ask your doctor or pharmacist for help.
Advantan® ointment, fatty ointment and cream
Apply thinly to the affected area of skin.
Apply thinly to the affected area of skin and gently rub in.
Treatment of eczema
Use Advantan® once a day to treat the affected skin.
Treatment of psoriasis
Use Advantan® ointment, fatty ointment or cream once or twice a day on the patches of psoriasis.
Usually, treatment with Advantan® is for up to 12 (twelve) weeks in adults and 4 (four) weeks in children.
Treatment with Advantan® should be for the shortest possible time period, and minimised to only on affected area. This is particularly important when using Advantan under bandages.
This is particularly important when treating large areas, and in children.
Excessive application of topical corticosteroids to large areas of the body for prolonged periods of time can increase the risk of side effects. Discuss this with your doctor.
If you forget to use Advantan®, use it as soon as you remember. Then go on as before.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to use your medicine, ask your doctor or pharmacist for some hints.
Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26 in Australia) for advice, or go to the Emergency Department at the nearest hospital, if you think that you or anyone else may have used too much or swallowed some of this medicine. Do this even if there are no signs of discomfort or poisoning.
If you use too much Advantan® or use it for a long time, you may notice the following in the treated area:
Stop using Advantan® if you have these symptoms and tell your doctor.
These symptoms usually disappear about two weeks after you stop using Advantan®.
Stop using Advantan® if you develop a skin allergy.
Tell your doctor if your skin becomes very dry when you use Advantan® cream or lotion. Your doctor may prescribe Advantan® ointment or fatty ointment instead.
If your eczema or psoriasis is infected, you must
If you are going to start any new medicine, tell your doctor and pharmacist that you are using Advantan®.
If you become pregnant while using Advantan®, tell your doctor immediately.
Do not use Advantan® to treat any other complaints unless your doctor tells you to.
Do not give your medicine to anyone else, even if they have the same condition as you.
See also the section with the heading Before you use Advantan®.
As with all medicines, Advantan® can cause some side effects. Side effects not listed in this leaflet may occur in some patients.
Do not be alarmed by the following list of side effects. You may not experience any of them.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor or pharmacist:
The above list includes the more common side effects.
The following list includes side effects that are rare:
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
Other side effects not listed above may also occur in some people.
Keep Advantan® in its pack until required.
Keep your Advantan® ointment or cream in a cool dry place where the temperature stays below 25 °C.
Keep your Advantan® fatty ointment or lotion in a cool dry place where the temperature stays below 30 °C.
Do not store Advantan® or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car.
Heat and dampness can destroy some medicines.
Keep Advantan® where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
Do not use Advantan® after the expiry date on the pack.
If your doctor tells you to stop using Advantan® or the expiry date has passed, ask your pharmacist what to do with any Advantan® that is left over.
Advantan® ointment is a white to yellowish, opaque ointment, with a firm consistency.
Advantan® fatty ointment is a white to yellowish, semi-clear ointment, which is greasier than Advantan® ointment.
Advantan® cream is a white cream, lighter in consistency than the ointments, and less greasy.
Advantan® lotion is a white lotion, more fluid than the cream.
Advantan® ointment contains 1 mg of methylprednisolone aceponate per gram of ointment as the active ingredient. It also contains
Advantan® fatty ointment contains 1 mg of methylprednisolone aceponate per gram of fatty ointment as the active ingredient. It also contains
Advantan® cream contains 1 mg of methylprednisolone aceponate per gram of cream as the active ingredient. It also contains
Advantan® lotion contains 1 mg of methylprednisolone aceponate per gram of lotion as the active ingredient. It also contains
Advantan® does not contain lactose, sucrose, gluten, tartrazine or any other azo dyes.
The Australian Registration Numbers are
Advantan® ointment AUST R 49381
Advantan® fatty ointment: AUST R 49382
Advantan® cream: AUST R 49380
Advantan® lotion: AUST R 80272
This is not all the information available on Advantan®. If you have any more questions or are unsure about anything, ask your doctor or pharmacist.
Advantan® is sponsored in Australia by:
ABN 99 051 588 348
45 Poplar Road
This leaflet was prepared in February 2008
Published by MIMS/myDr August 2008