Short-course steroids appear to be safe for bones
14 February 2003
Children who are treated with repeated short courses of oral corticosteroids for acute asthma exacerbations have normal bone mineral density, Canadian research shows.
Data from 83 children with asthma showed those who received up to 11 bursts of steroids in one year did not develop osteopenia (decreased bone density) or suppression of adrenal gland function. But the researchers said children receiving successive courses over a short time should be screened for adrenal suppression (Pediatrics 2003; 111: 376-83).
Children treated with repeated bursts of steroids had greater than expected height and weight, suggesting steroid bursts don't affect growth.
While these results alleviate some safety concerns about repeated steroid use, adequate preventive therapy is preferable, the researchers noted.
Last Reviewed: 14 February 2003
- 1. Medical Observer Weekly 14/02/03
