Celandine herb may have toxic liver effects
13 June 2003
Liver toxicity is a potential side effect of the herb greater celandine (Chelidonium majus), the Therapeutic Goods Administration (TGA) has said after a preliminary safety review.
The herb is used to treat liver conditions as well as stomach pain, warts, hepatitis, cataracts and headaches.
'[We] examined the evidence on the association between the use of the herb and liver toxicity and noted the fact that, in Germany, where most of the published cases had been reported, the herb remained on the market with a warning about risks of liver problems,' the TGA said.
A decision about implementing stronger controls would not be made until the full safety profile had been completed, the TGA said.
A letter to The Lancet (2002; 360: 1336), citing 15 cases of liver damage following celandine use, alone or in combination with other herbs, initiated the TGA review.
Last Reviewed: 11 June 2003
- 1. Medical Observer Weekly 13/6/03
