NSAIDs and arthritis
Many people with chronic arthritis are helped by taking one of the non-steroidal anti-inflammatory drugs, known for short as NSAIDs.
There are many medications in this group. Among them are naproxen (e.g. Naprosyn), ibuprofen (e.g. Brufen), piroxicam (e.g. Feldene), diclofenac (e.g. Voltaren), ketoprofen (e.g. Orudis) and indomethacin (e.g. Indocid). Taking these medications can reduce the pain of arthritis, reduce joint stiffness and improve mobility.
Unfortunately, these medications can irritate the stomach lining, causing indigestion and even producing ulcers. For this reason they should always be taken during, or immediately after, a meal.
Many people take these medications for long periods without experiencing any problems. But for those who are susceptible to stomach problems, there is some good news.
A study in the UK has shown that if patients on long-term treatment with NSAIDS also took anti-ulcer tablets on a regular basis, their chance of developing an ulcer was reduced from about one in 3 to less than one in 10.
Many patients have been worried by publicity about the side effects of NSAIDs. These drugs are not necessary for all cases of arthritis and other ways of treating the problem should always be considered.
However, there is no doubt that for many people NSAIDs can greatly improve their quality of life.
The latest treatments for arthritis, the coxibs or COX-2 inhibitors and the COX-2 selective inhibitors, may be suitable for some people with arthritis. They are believed to have fewer gastrointestinal side effects than conventional NSAIDs, but may be associated with other risks. Your doctor can advise you on the risks and benefits of these medications.
If you are taking any of the above-mentioned medications, discuss possible side effects with your doctor.
Last Reviewed: 16 May 2005
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